The Problems with the Lombardi et al 2009 Science paper

Some of the problems of the Lombardi et al. 2009 Science paper, many of which should have been addressed prior to publication.

- Failure to state if samples were tested in a blinded fashion
- Failure to state the reason that not all tests were done on all samples
- Failure to sufficiently describe each employed test method
- Mislabeling of at least one slide
- Omission of the usage of 5AZA
- Failure to publish full viral gene-sequences
- Failure to show genetic variation expected of a retroviral pathogen vs. contamination
- Failure to show integration into the human genome

Plus Mikovits communicated tidbits about the study on her talks, instead of publishing them.

[Update]
Furthermore I would add these points:
- Failure to explain the rational to use nested PCR
- Failure to account for higher risk of contamination with nested PCR the way PCR was used

[Update]
- Usage of water only negative control samples
- Failure to report the use of positive control samples
- Failure to discuss the PCR sensitivity

[Update]

- again: Failure to report the use of positive control samples

- Failure to show control results of PCR without reverse transcriptase (RT) for detection of DNA (plasmid) contamination

[Update]
- Failure to supply a all test results for each sample (patients and controls)

[Update]
- The main result (67% PCR positive) is shown in one (!) sentence, without any supporting material