As Moore and Shuda noted, Mikovits's group used a technique called “nested PCR” to identify XMRV infections, which, they wrote, “is inherently prone to intermittent false positivity that has occurred in our lab and many others.” What's more, the researchers had not randomized and blinded patient and control samples, a standard way to protect against bias and to detect errors. Together, Moore and Shuda wrote, this was “a recipe for uncontrolled PCR contamination.”Or for controlled PCR contamination, as a matter of fact.
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