Grand total 1374 potential pathogens, counting Salmonella once. This is, obviously a gross estimate, probably a gross underestimate, of the number of pathogens that can infect us. Obviously, not everyone is exposed to every one of these pathogens. Keep in mind that each organism makes dozens of proteins and carbohydrates for the immune system to recognize and to respond with a specific antibody. I would bet the list represents more than 13,740 antibodies.This reservoir of 10k of antigens/antibodies is a reservoir for molecular mimicry like auto-immune problems, as far as I understand it. What I don't understand: we should have with micro-assays now the tools to screen auto-immune diseases for identity of auto-immune antibodies to anti-pathogen anti-bodies.
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