Just a short anecdote: I recently ran an natural experiment. I wanted to see if removing all fructose from my diet (and therefore all sucrose as well) would have an (hopeful positive) impact on my health. As I need some sweetness in coffee, and as coffee with pure dextrose ("glucose") tastes like dish water, I used some artificial sweetener as well (in tablet form, that my mother had bought for herself).
After maybe a week or two of using this sweetener, with maybe some 6 to 8 tablets a day, I noticed an pathological increase of my libido, something I have not had since I reduced dairy in 2010. What was wrong? What was different? What the hell had I eaten? Of course the sweetener! Duh. Checking the little ingredient list on the bottle, written in that tiny tiny font, what did my eyes see? Lactose.
I have then exchanged the tablet sweetener (with lactose) for a similar one in liquid form (sans lactose, with a tab bit of fructose). And all is well again (at least considering THAT problem).
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