Wednesday, September 26, 2012

Is ME/CFS an mental illness – an comment

I made an comment at an (otherwise not noteworthy) article:
Three researchers – Mikovits, Ruscetti and Lombardi – published one (possibly fraudulent) study, a study that didn't help up to scrutiny – that doesn't mean that ME/CFS is an mental illness.

You should look into the work of Alan Light, a Research Professor of Anesthesiology at the University of Utah.

His topics are:
- Cellular Neuroscience
- Neurobiology of Disease
- Molecular Neuroscience
- Brain and Behavior

He has done some research into pain (and now fatigue) of – among other diseases – ME/CFS. His work shows differential gene expression in peripheral blood cells of ME/CFS patients after an exercise challenge – this indicates increase pain and fatigue in sensory nerve endings at the muscle level.

Two of his lectures (available on YouTube) are in my view recommendable to come up to speed to his research:

2007 Lecture: "The Physiology of Chronic Pain and Fatigue"

2011 Lecture: "Gene Expression Biomarkers for Chronic Fatigue & Fibromyalgia Syndromes"

In my opinion the findings by Alan Light rule out mental illness as an probable disease model for ME/CFS.
[I reworked the comment slightly for this blog]

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