Remission without insulin therapy on gluten-free diet in a 6-year old boy with type 1 diabetes mellitus.Yes indeed, further trials are indicated.
Sildorf SM, Fredheim S, Svensson J, Buschard K.
Paediatric Unit, Copenhagen University Hospital, Herlev, Denmark.
A 5-year and 10-month old boy was diagnosed with classical type 1 diabetes mellitus (T1DM) without celiac disease.
He started on a gluten-free diet after 2-3 week without need of insulin treatment.
At the initiation of gluten-free diet, HbA1c was 7.8% and was stabilised at 5.8%-6.0% without insulin therapy.
Fasting blood glucose was maintained at 4.0-5.0 mmol/l.
At 16 months after diagnosis the fasting blood glucose was 4.1 mmol/l and after 20 months he is still without daily insulin therapy.
There was no alteration in glutamic acid decarboxylase positivity.
The gluten-free diet was safe and without side effects.
The authors propose that the gluten-free diet has prolonged remission in this patient with T1DM and that further trials are indicated.