Friday, January 20, 2012

How many different antibodies for an retrovirus like HIV?

Each bacteria has multiple sites that can elicit an antibody response. It is not one organism, one antibody. The number of antibodies that the body develops against a germ depends on the the complexity of the organism which in turn determines how many antibodies are made against a particular organism. We use the multiple antibodies made for some organisms diagnostically. For a simple organisms like HIV, we do a western blot and look for the presence of an antibody response to 8 different proteins. For Lyme, we look for antibody response to 10 proteins. For more complex organism like S. aureus we can make dozens of different antibodies. 
Posted by Tony Mach Posted on Friday, January 20, 2012
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