Saturday, January 14, 2012

A message to Jamie Deckoff-Jones MD - Why antiretrovirals are a horrendously stupid idea without a quantitative test

Imagine you aren't feeling well. You go to the doctor, they run some tests, and it turns out you have a tumor. Well... your physicians aren't sure if you have a tumor or not, but they sent some of your blood to a lab, and a non-FDA approved test said you might have a tumor. Maybe. When your blood was sent to other labs, they couldn't find anything.

And even if you do have a tumor, you have no reason to believe that its actually causing a disease-- it very well could be benign. They dont know how its effecting you, if at all. Technically, they dont even know where it is.

But good news! They have a drug that works on these kinds of tumors in tissue culture... but no one has tested these drugs on your kind of tumor in small animal models, much less non-human primates, much less valid clinical trials on humans.

And even if you take this drug, there is no way of objectively measuring whether it is working or not. Technically, it could be making the tumor worse, but again, we can't measure 'better' or 'worse' objectively, so...

Oh, and btw, the drug they have to 'treat' you has severe side-effects. A 'successful' treatment course will almost certainly ultimately lead to liver and/or kidney failure (assuming you aren't hit by a car before then), plus a host of other side effects along the way.

Would you take this drug for your 'tumor'?

Now read the text above, but replace 'a tumor' with 'XMRV'. Would you confidently take antiretrovirals?

Far too many Chronic Fatigue patients are, and I will try to explain exactly why this is a horrible, horrible idea
Oh, I am sure Jamie Deckoff-Jones will refuse to acknowledge this in any meaningful way, as she always does with reality.
That is not how science works. Thats how we get drug resistant XMRV right out of the starting gate, assuming it is a real, harmful pathogen. You would think that someone like Judy Mikovits would understand basic fucking retroviral population biology, and would speak out, LOUDLY, against this, but apparently she is a moron on many, many, many levels.
Posted by: ERV | June 14, 2010 8:10 PM
And this makes it ever more so clear why they pushed their shitty cytokine-profiles study – they need some form of test to push an anti-retroviral treatment. Sorry, this is not scientific, this confirmation-bias driven woo.

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