This is one possible scenario – don't know how likely it is.
Someone at W labs contaminated the patient samples with plasmid. Either Dr. M or Dr. L did it.
Dr. S was duped into doing some PCR&sequencing with samples contaminated with plasmid. But most PCR&sequencing was done at W labs, or at the Genomics Center of the same university of which W labs shares the campus. I think neither Dr. S, nor the Genomics Center did anything wrong except being duped.
Dr. R and his lab got on board to do the serology once the PCR was already going (don't know, needs checking) and showing positive patient samples by PCR. But one possible scenario was that Dr. R's lab didn't find positive serology. So if X was a real pathogen, and they fudged the results to show positive serology, nobody would ask questions how correct the results were – history would prove them right, after all, and they'll get fame and fortune. This would not have been necessarily been Dr. R, it could have been a postdoc feeling the pressure to come up with positive serology results.
Now let's look at Dr. L. He had a strong incentive to come up with the diagnostic test for X at V labs. If he was the one doing the plasmid thing at W lab, he knew what to do at V lab. If on the other hand Dr. M did the plasmid thing at W lab, he would be under pressure to come up with a test at V lab that would produce positive results.
I think Dr. M works alone. It is my impression that Dr. M does not play along with others. Whatever Dr. M did, I think she did not coordinate with Dr. L. And if Dr. L did it, he would not have told it to Dr. M – that's for sure. So did it Dr. M dupe Dr. L? Or did Dr. L dupe Dr. M? Or did they both do something independently, duping each other?
Dr. L was either really stupid and got results at V lab by accidental contamination – something I can't rule out. Or he must have known what was going on.
Dr. M showed initially 100% confidence in the results of V lab's testing, but after being fired discard the results of V lab. Equally, Dr. M showed initially 100% confidence in the results of PCR&sequencing, but then discarded the results of PCR testing and sequencing. The only thing Dr. M seems to confident of is the serology done at Dr. R's lab – Dr. M basically discarded everything done by Dr. M or Dr. L, done at W lab or done at V lab.
I think Dr. M knows that everything done at W lab or V lab was fake – and Dr. M does not know what happened at Dr. R's lab – that is why Dr. M thinks that X/M/P/whatever is a human pathogen, because Dr. R's lab found something. But as shown above, that could have been Dr. R's lab just playing along and fudging the results for fame and fortune.
So who was it? Was it Professor Plum in the library with the candlestick? I guess we'll need to have a bit more information first…
Plus, we should factor in the housing crisis that started in 2008 (and the problems were felt at least one year before) and probably affected the W's and put pressure on the W lab.
Saturday, February 11, 2012
5-AZA A. Melvin Ramsay Acne Advocacy Alan Light Alternative medicine is an untested danger Ampligen Andrew Wakefield Anecdote Anthony Komaroff Antibiotics Antibodies Anxiety Aphthous Ulcers Apnea Asthma Autism Autoimmune Disease Behçet’s Ben Katz Bertrand Russell Biology Blood sugar Bruce Carruthers Caffeine Calcium Cancer Capitalism Cardiology Carmen Scheibenbogen CBT/GET CDC Celiac Disease Cereal Grains CFIDS Chagas Charité Charles Lapp Christopher Snell Chronix Clinician Coconut Milk Cognition Common Sense and Confirmation Bias Conversion Disorder Coxiella Burnetii Coxsackie Criteria Crohn's Cushing's Syndrome Cytokine Daniel Peterson Darwinism David Bell Depression Diabetes Diagnostic Differential Disease Diseases of Affluence DNA DNA Sequencing Dog DSM5 EBV EEG Eggs Elaine DeFreitas Elimination Diet Enterovirus Epstein-Barr ERV Etiology Evolution Exercise Challenge Faecal Transplant Fame and Fraud and Medical Science Fatigue Fatty Acids Fibromyalgia Francis Ruscetti Fructose Gene Expression Genetics Giardia Gordon Broderick Gulf War Illness Gut Microbiome Harvey Alter Health Care System Hemispherx Hemolytic Uremic Syndrome Herpesviridae High Blood Pressure Historic Outbreaks HIV HPV Hyperlipid Ian Hickie Ian Lipkin Immune System Infection Intermittent Fasting It's the environment stupid Jacob Teitelbaum Jamie Deckoff-Jones Jo Nijs John Chia John Coffin John Maddox José Montoya Judy Mikovits Karl Popper Kathleen Light Kenny De Meirleir Lactose Lamb Laszlo Mechtler LCMV Lecture Leonard Jason Leukemia Life Liver Loren Cordain Low Carb Low-Dose Naltrexone (LDN) Luc Montagnier Lucinda Bateman Ludicrous Notions Lumpers and Splitters Lyme Mady Hornig Mark Hasslett Martin Lerner Mary Schweitzer MCS ME/CFS Medical Industry Medicine is not based on anecdotes Michael Maes Migraine Milk and Dairy Mitochondria MMR Money and Fame and Fraud MRI Multiple Chemical Sensitivity Multiple Sclerosis Mutton My Symptoms n-1 Nancy Klimas Narcolepsy Neurodermitis Neuroscience NK-Cell Nocebo NSAID Nutrition Obesity On Nutrition Pain Paleo Parathyroid Pathogen Paul Cheney PCR Pharmaceutical Industry Picornavirus Placebo Polio Post Exertional Malaise POTS/OI/NMH PTSD PUFA Q Fever Quote Rare Disease Research Retrovirus Rheumatoid Arthritis Rituximab RNA Robert Gallo Robert Lustig Robert Silverman Robert Suhadolnik Rosario Trifiletti Sarah Myhill Sarcasm Science Sequencing Seth Roberts Shrinks vs. Medicine Shyh-Ching Lo Simon Wessely Sinusitis Sjögren's Somnolence Sonya Marshall-Gradisnik Speculation Stanislaw Burzynski Statins Stefan Duschek Study Sucrose Sugar Supplements Symptoms T1DM T2DM There is no such thing as Chronic Lyme There is no such thing as HGRV Thyroid Tinitus To Do Toni Bernhard Tourette's Treatment Tuberculosis Vaccine Video Vincent Lombardi Vincent Racaniello Virus Vitamin B Vitamin D VP62 When Evidence Based Medicine Isn't Whooping Cough Wolfgang Lutz WPI XMRV You fail science forever